Ulcerative colitis is a chronic disease that causes inflammation and ulcers in the lining of the colon and rectum. The main symptom of active disease is abdominal pain and cramping, bloody diarrhea, and weight loss.
Ulcerative colitis can be debilitating and sometimes leads to life-threatening complications. The exact cause of ulcerative colitis is unknown. It is thought to be an autoimmune disorder, in which the body's immune system attacks the lining of the colon for unknown reasons. Ulcerative colitis is not contagious.
Asacol is a medication used to treat ulcerative colitis, a condition in which the lining of the colon becomes inflamed. The active ingredient in Asacol, mesalamine, works by reducing inflammation in the colon.
Asacol is available in both tablet and enema form. The enema is inserted into the rectum, where it is absorbed into the colon. The tablet is taken orally.
The brand name was discontinued in the United States in 2013, but the drug is still available in generic form. The exact reason for the discontinuation of Asacol is unknown, but it is likely due to a combination of factors. One reason may be that the patent for the drug expired in 2012, making it available as a generic.
Generic drugs are typically cheaper than brand-name drugs, so there was likely little financial incentive for the company to keep the brand name on the market.
Another reason for the discontinuation may be that there are other, similar drugs available that are just as effective as Asacol but have fewer side effects. For example, Lialda (mesalamine) is a newer drug that is similar to Asacol but causes less diarrhea. Because of this, Lialda may be a more attractive option for patients.
Asacol was a popular drug for the treatment of ulcerative colitis, but its discontinuation is not likely to have a major impact on patients. Learn Why was Asacol Discontinued.
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